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Symbol Name ID |
Atp2a2
ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 MGI:88110 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Human Phenotypes | Elevated diastolic blood pressure |
Elevated mean arterial pressure |
Elevated systolic blood pressure |
| Disease(s) Associated with ATP2A2 | |||
| essential hypertension |
| Mouse Phenotypes | cardiovascular system phenotype |
ascending aorta hypoplasia |
aorta coarctation |
abnormal vascular development |
abnormal physiological neovascularization |
decreased angiogenesis |
abnormal vascular endothelial cell migration |
thin ventricle myocardium compact layer |
heart left ventricle hypertrophy |
abnormal heart left atrium morphology |
atrial septal defect |
dilated heart atrium |
increased heart left ventricle septal wall thickness |
ventricular septal defect |
globular heart |
increased heart weight |
enlarged heart |
cardiac hypertrophy |
increased heart left ventricle posterior wall thickness |
dilated heart left ventricle |
dilated heart right ventricle |
cardiac fibrosis |
cardiac interstitial fibrosis |
abnormal cardiovascular system physiology |
abnormal blood circulation |
decreased cardiac output |
decreased cardiac muscle contractility |
decreased ventricle muscle contractility |
abnormal cardiac muscle relaxation |
abnormal heart left ventricle pressure |
decreased left ventricle systolic pressure |
increased left ventricle diastolic pressure |
decreased heart rate |
abnormal myocardial fiber physiology |
increased response of heart to induced stress |
decreased systemic arterial blood pressure |
decreased systemic arterial systolic blood pressure |
abnormal vascular endothelial cell physiology |
congestive heart failure |
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| Availability | Mouse Genotype | |||||||||||||||||||||||||||||||||||||||
| Atp2a2tm1.1Raco/Atp2a2tm1.1Raco | ||||||||||||||||||||||||||||||||||||||||
| Atp2a2tm1Fwuy/Atp2a2tm1Fwuy | ||||||||||||||||||||||||||||||||||||||||
| Atp2a2tm1.1Raco/Atp2a2+ | ||||||||||||||||||||||||||||||||||||||||
| Atp2a2tm1Ges/Atp2a2+ | ||||||||||||||||||||||||||||||||||||||||
| Atp2a2tm1.1Iemr/Atp2a2tm1.1Iemr A1cfTg(Myh6-cre/Esr1*)1Jmk/A1cf+ (conditional) |
* | |||||||||||||||||||||||||||||||||||||||
| Atp2a2tm1.1Iemr/Atp2a2+ Myl2tm1(cre)Krc/Myl2+ (conditional) |
* | |||||||||||||||||||||||||||||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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